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Wednesday, December 7, 2016
Chemotherapy is usually associated with a collection of side effects ranging from digestive problems to hair loss, but a study published this week in Human Reproduction demonstrated that female cancer patients may find they have something in common with much younger women in one specific area — their ovaries.
Scientists from the University of Edinburgh examined donated ovarian tissue from fourteen female cancer patients, most of whom had Hodgkin lymphoma, and compared it to tissue from healthy women. They found the samples from women who had been treated with a specific chemotherapeutic regimen known as ABVD not only contained greater numbers of dormant ova — egg cells — than those from women treated with harsher regimens but also more than samples from healthy women. ABVD is named for combining several drugs known as adriamycin, bleomycin, vinblastine, and dacarbazine.
These reproductive cells were not merely more plentiful in ABVD patients. They also appeared immature, “new” in the words of lead researcher Evelyn Telfer. This challenges the conventional belief that girls are born with all the ova they will ever have and the numbers can only go down as the cells are either used up by the reproductive cycle or succumb to damage or natural aging. However, further research is needed to confirm this. The study covered relatively few patients by scientific standards, and David Albertini of the Center for Human Reproduction in New York has suggested the cells may not actually be freshly grown. Instead, they may have always been there and were merely rendered more detectable by ABVD treatment.
The ability to grow new egg cells may have significant implications for women in Western societies, many of whom postpone childbearing to establish careers, sometimes into their late thirties or forties. However, Telfer warns against making use of these findings too soon: “There’s so much we don’t know about the ovary. We have to be very cautious about jumping to clinical applications.”
The experiments had been discussed earlier this year at the annual conference of the European Society of Human Reproduction and Embryology.
Sunday, September 28, 2008
A fire on Saturday destroyed the main hall of the Egyptian National Theatre in Cairo. Six people have been injured including three firefighters. No one was in the theatre at the time as it was closed for the weekend.
Egyptian state culture minister Faruq Hosni, said “The fire broke out in the main hall of the theatre. It was probably caused by an electrical short circuit.”
Ataba Square was filled with thick white smoke just after sunset as a total of 22 fire engines responded. Egyptian riot police were also deployed to keep crowds of people back while the firefighters attempted to extinguish the blaze.
A civil defence officer described the fire as being almost contained, following a brief burst of high winds which blew the flames towards neighbouring shops and other buildings. The three firefighters were admitted to hospital suffering from the effects of smoke inhalation.
Brig. Gen. Nasr Zakaria, a senior officer of the Civil Defence Service, later confirmed Minister Hosni’s earlier statement, telling MENA (Middle East News Agency) that an electrical short had indeed caused the fire, by triggering an explosion in the theatres air conditioning system.
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Monday, April 25, 2005
With two space walks, 78 million miles and six months on board the International Space Station under their belts, Commander-Science Officer Leroy Chiao and Flight Engineer Salizhan Sharipov, the station’s 10th crew, landed in Kazakhstan in a Soyuz spacecraft at 6:08 p.m. EDT Sunday.
Also returning was European Space Agency Astronaut Roberto Vittori of Italy, who launched to the Station with the Expedition 11 crew and spent eight days doing experiments. He was aboard under a contract between ESA and the Russian Federal Space Agency.
The re-entry of the ISS Soyuz 9 spacecraft was perfect, returning the astronauts to Earth 53 miles northeast of the town of Arkalyk after 192 days, 19 hours and 2 minutes in space for the Expedition 10 crew. The recovery team reached the capsule in minutes.
They launched from the Baikonur Cosmodrome in Kazakhstan last Oct. 13 at 11:06 p.m. EDT. During their increment they performed two spacewalks, continued station maintenance and did scientific experiments.
Notable accomplishments included replacing critical hardware in the Joint Quest Airlock; repairing U.S. spacesuits; and submitting a scientific research paper on ultrasound use in space. Chiao was also the first astronaut to vote in the U.S. Presidential election from space. The crew completed two spacewalks, including experiment installation and tasks to prepare the Station for the arrival of the new European Automated Transfer Vehicle next year.
Aboard the Station, Commander Sergei Krikalev and Flight Engineer and NASA Station Science Officer John Phillips, the Expedition 11 crew, are beginning a six-month mission. It will include the resumption of Space Shuttle flights and two spacewalks from the Station. Expedition 11 is scheduled to return to Earth on October 7, 2005. The two latest occupants of the station launched with Vittori from Baikonur April 14.
Krikalev and Phillips will have light duty for the next two days, as they rest after completing a busy handover period. For the past week, they have been learning about Station operations from the two men who called the ship home since October. Chiao and Sharipov briefed Krikalev and Phillips on day-to-day operations and gave them hands-on opportunities at Station maintenance. Chiao and Phillips restored the Quest airlock to working order for future spacewalks and practiced operating the Canadarm2 robotic arm.
Overuse, Injury, and conditions that cause inflammation of the bones or ligaments in the foot can cause you to experience foot pain. There are a lot of different conditions that can cause you to experience severe foot pain. Arthritis is one of the most common reasons individuals experience pain in their feet. Nerve injuries may cause a burning sensation in your feet and sometimes even tingling or numbness. Here are a few of the most common conditions that cause foot pain.
A bunion is a bony bump that will form on your big toe right at the base. It is caused when your big toe presses against the toe next to it forcing your toe’s joint to get much bigger and become sore and red. If you have a painful bunion you should not wear narrow or tight shoes as they may cause you to experience more pain and make your bunion worse.Bursitis
Bursitis is a condition that impacts the small sacs that keep your bones and muscles in your joints cushioned. Bursitis takes place when that area called the bursae then becomes inflamed. The typical areas you can experience bursitis is in the elbow, hip, and shoulder. However, bursitis does occur in the heel and your big toe.
Calluses and Corns
Corns and calluses are hardened, thick, skin layers that occur when the skin of your feet try to protect itself from pressure and friction. These typically occur in hands, feet, as well as the toes. Corns and calluses can typically be treated from home unless they are causing you a great deal of pain or you suffer from diabetes. If this is the case for you then you should see a foot doctor in Chicago and let them take a look.
Gout is a more complex form of arthritis that causes severe pain in certain joints in the body. If you have gout you typically experience severe pain attacks and tenderness and redness in the joints, typically right at the base of your large toe.
There are times where you wake up and are experiencing a severe burning sensation at the base of your toe that makes it feel as though it is on fire. The good news is that gout is treatable by your podiatrist.
If you are experiencing any foot pain, even ones not listed here, you need to see your podiatrist as soon as possible.
If you are looking for a reliable foot doctor in Chicago Kondiles Chicagoland Footcare can help. Visit their website to learn more.
A compilation of brief news reports for Wednesday, September 3, 2008.
The United States military has handed Anbar province, once the centre of Iraq’s Sunni insurgency, to Iraqi control at a ceremony in the provincial capital. For Iraqi politics, the Anbar handover is especially meaningful because the Shiite-dominated Iraq military will now provide security in a largely Sunni province. Anbar is the eleventh of 18 provinces that the coalition has returned to Iraqi control, but it is the first Sunni province. President George W. Bush said that “Today, Anbar is no longer lost to al-Qaeda, it is al-Qaeda that lost Anbar.”
- Patrick Cockburn. “US hands control of Anbar province to Iraqi military” — The Independent, September 2, 2008
- “Victory in Anbar” — The Wall Street Journal, September 2, 2008
- “US hands over key Iraq province” — BBC News Online, September 1, 2008
Stanford University has developed an artificial intelligence software that allows their model helicopters to learn complex aerial acrobatics simply by “watching” a human. The human controlled helicopter is monitored by a variety of sensors which funnel all the data into the AI software. Once the acrobatic trick has been repeated a few times, the computer analyzes the data. It is then capable of repeating, with greater accuracy than the human controller, the acrobatics. This system allows the helicopters to preform aerial maneuvers far more complicated than previously possible.
- “‘Autonomous’ Helicopters Teach Themselves To Fly” — Science Daily, September 2, 2008
- Dan Stober. “Stanford’s “autonomous” helicopters teach themselves to fly” — Stanford News Service, August 29, 2008
A Malaysian man, who was about to be engaged, attempted to use a nut to weigh down and elongate his penis. Once he got an erection, the nut became stuck and he was unable to remove it. He sought treatment at a local hospital where they were able to remove it. He is expected to be released from the hospital shortly.
- “Malaysian man gets nut stuck in delicate place” — China Daily, September 2, 2008
- AFP. “Malaysian man gets nut stuck in delicate place: report” — Yahoo! News, August 31, 2008
Thursday, February 12, 2009
An article in the February 12 issue of the New England Journal of Medicine reports on an unusual cause for an outbreak of low blood sugar among men in Singapore: illegal use of sexual performance enhancement drugs that were contaminated with a diabetes drug.
Between January and May 2008, 149 men and one woman between 19 and 97 (mean age 51) were admitted to five public hospitals for unexplained low blood sugar. Similar cases were reported in media reports from Hong Kong. Seven Singaporean patients remained in a coma because of prolonged sugar starvation of the brain, and four subsequently died. The diabetes drug glyburide was found in blood and/or urine samples in 85% of cases; 30% admitted having used illegal sexual performance enhancers.
The contaminated products were a counterfeit version of the drug Cialis (meant for the treatment of genuine erectile dysfunction), and three purported herbal preparation (the affected brands included Power 1 Walnut and Santi Bovine Penis Erecting Capsule). All four preparations additionally contained Viagra in varying concentrations. Two herbal products contained traces of the weight loss drug sibutramine, a compound related to amphetamines.
The drug packaging mentioned names of non-existent overseas production facilities, so the source of the contamination with the diabetes drug could not be established.
The authors underline the risks that is known to be associated with purchasing drugs from unreliable providers or from online resellers. The clandestine use of impotence drugs as sexual performance enhancers seems to have provided a good illustration of this problem. They further call for more efforts by national and international health and law enforcement agencies to curb the manufacturing, international transport and sales of untrustworthy medication.